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, PharmD, PhD, BCPS
Department of Pharmacotherapy & Outcomes Science
Smith Building, Room 652B
School of Pharmacy
Dept of Pharmacotherapy & Outcomes Science
410 N 12
P.O. Box 980533
Richmond, VA 23298-0533
Area of Focus
Blood brain barrier
Drugs of Abuse
Pharm.D., (Virginia Commonwealth University, 2000)
Ph.D., Pharmaceutical Sciences (University of North Carolina at Chapel Hill, 2005)
(2006 - 2011) Assistant Professor, Department of Pharmacology, Kansas City University of Medicine and Biosciences
(2011 - 2012) Associate Professor, Department of Pharmacology, Kansas City University of Medicine and Biosciences
(2012 - Present) Assistant Professor, Department of Pharmacotherapy and Outcomes Science, VCU School of Pharmacy
Professional and Scholarly Interests
American Society of Clinical Pharmacology and Experimental Therapeutics
Clay PG, McRae M, Laurent JP. Safety, Tolerability, and Pharmacokinetics of KP-1461 in Phase I Clinical Studies: A Single Oral Dose Study in Non-HIV-Infected Adults, and a 14-Day Dose-Escalating Study in Highly Antiretroviral-Experienced HIV-Infected Adults, J Int Assoc Physicians AIDS Care, 2011 Jul-Aug; 10(4):232-8.
Clay PG, Adiga R, Taylor TAH, Alsup R, Gerk PM, McRae, MP. Postpartum Pharmacokinetics of Peramivir in the Treatment of Influenza H1N1: A Case Report, Obstetrics & Gynecology, 2011 Aug; 118(2 Pt 2):463-7.
Hicks C, Clay P, Redfield R, Lalezari J, Liporace R, Ramirez JM, Schneider S, Sension M, DeGruttola V, Hughes J, McRae MP, Laurent JP, Safety, Tolerability and Efficacy of KP-1461 as Monotherapy for 124 Days in Antiretroviral-Experienced, HIV-1-Infected Subjects. AIDS Research and Human Retroviruses, 2012 Jun 28.
Dever, SM, Costin BN, Xu R, El-Hage N, Balinang J, Samoshkin A, O’Brien MA, McRae MP, Diatchenko L, Knapp PE, Hauser KF. 2013. Differential expression of the alternatively-spliced OPRM1 isoform MOR-1K in HIV-infected Subjects. AIDS, 2014 Jan 2; 28(1):19-30.
Ellis K, Marlin JW, Taylor TA, Fitting S, Hauser KF, Rice G, McRae M. The effects of human immunodeficiency virus infection on the expression of the drug efflux proteins P-glycoprotein and breast cancer resistance protein in a human intestine model. J Pharm Pharmacol, 2014 Dec 31. [Epub ahead of print]