vcu bar

Michael Hindle, Ph.D.


Peter R. Byron Distinguished Professor
Professor

Department of Pharmaceutics

Location:  Smith Building, Room 442
Phone: (804) 828-6497
Email: mhindle@vcu.edu
Web: Research Website

Mailing Address

School of Pharmacy - Dept of Pharmaceutics
410 N 12th Street
P.O. Box 980533
Richmond, VA 23298-0533
Fax: (804) 828-8359


Education

  • Ph.D., Pharmaceutical Sciences (University of Bradford in U.K., 1992)
  • B.S., Pharmacy (University of Bradford in U.K., 1989)

Post-Graduate Training

  • Post Doctoral Fellow - Pharmaceutics (Department of Pharmaceutics, School of Pharmacy, Virginia Commonwealth University, 1994)

Academic Appointments/Professional Experience

  • 1995-1996. Lecturer, Department of Pharmaceutical Sciences, University of Bradford, Bradford, U.K.
  • (1997 - 2016) Research Associate Professor, Department of Pharmaceutics, Virginia Commonwealth University
  • (2016 - Present) Professor, Department of Pharmaceutics, Virginia Commonwealth University

Research Interests

  • Novel aerosol drug delivery devices
  • In vitro particle size analysis
  • Aerosol characterization and inhaler design

Publications

PubMed Search
The publications search is performed on the National Library of Medicine's PubMed database. The search may be slow during high traffic hours, may return articles authored by another researcher with a similar name and may not always find all of a researcher's articles.


  • Books/Book Chapters
    • Hindle M: “Aerosol Drug Delivery”. In: Pharmaceutical Manufacturing Handbook (Eds Gad SC). John Wiley and Sons Inc., Hoboken, NJ, ISBN: 978-0-471-21391-8, pp 683-728, 2008.
  • Patents
    • Hindle, M and Cox, K.A., “Liquid aerosol formulations containing insulin and aerosol generating devices and methods for generating insulin aerosols”, US Patent # 7,683,029. Issued 2010.
    • Byron PR, Hindle M: “Method and Apparatus for Generating an Aerosol”, US Patent # 7,128,067 B2 Issued 2006.
    • Hindle M, Byron PR and Gupta R: “Method for generating an aerosol with a predetermined and/or substantially monodispersed particle size distribution,” United States Patent 6,883,516, 2005.
    • Longest PW and Hindle M “Delivery of Submicrometer and Nanometer Aerosols to the Lungs Using Hygroscopic Excipients or Dual Stream Nasal Delivery”. US Patent # 9,433,588. Issued 2016
    • Longest PW, Xi J, and Hindle M. “Effective delivery of nanoparticle and micrometer sized pharmaceutical aerosols to the lung through enhanced condensational growth". US Patent # 8,479,728. Issued 2013
  • Recent Publications
    • Longest PW, Rygg A, Hindle M: Bioequivalence Testing: Can Systemic Pharmacokinetic Profiles from Corticosteroid Nasal Sprays Be Used to Elucidate Local Drug Deposition within the Nose? Respiratory Drug Delivery 2016. 1: 175-184.
    • Rygg A, Hindle M, Longest PW: Absorption and Clearance of Pharmaceutical Aerosols in the Human Nose: Effects of Nasal Spray Suspension Particle Size and Properties. Pharm Res. 2016;33(4):909-21.
    • Longest PW, Tian G, Khajeh-Hosseini-Dalasm N, and Hindle M: Validating Whole-Airway CFD Predictions of DPI Aerosol Deposition at Multiple Flow Rates. J Aerosol Med Pulm Drug Deliv. 2016; doi:10.1089/jamp.2015.1281.
    • Rygg A, Hindle M, Longest PW: Linking Suspension Nasal Spray Drug Deposition Patterns to Pharmacokinetic Profiles: A Proof-of-Concept Study Using Computational Fluid Dynamics. J Pharm Sci. 2016;105(6):1995-2004.
    • Azimi M, Longest P, Hindle M: “Towards Clinically Relevant In Vitro Testing of Locally Acting Nasal Spray Suspension Products”, RDD Europe 2015. 1: 121-130, 2015.
    • Longest PW, Golshahi L, Behara SR, Tian G, Farkas DR, and Hindle M: Efficient Nose-to-Lung (N2L) Aerosol Delivery with a Dry Powder Inhaler. J Aerosol Med Pulm Drug Deliv. 2015;28:189-201.
    • Holbrook L, Hindle M, and Longest PW: Generating charged pharmaceutical Aerosols intended to improve targeted drug delivery in ventilated Infants. J. Aerosol Sci. 2015;88:35-47.
    • Golshahi L, Longest PW, Holbrook L, Snead J, and Hindle M: Production of Highly Charged Pharmaceutical Aerosols Using a New Aerosol Induction Charger. Pharm Res. 2015;32(9):3007-3017.
    • Farkas DR, Hindle M, and Longest PW: Characterization of a New High-Dose Dry Powder Inhaler (DPI) Based on a Fluidized Bed Design. Ann Biomed Eng. 2015;43(11):2804-2815.
    • Walenga RL, Tian G, Hindle M, Yelverton J, Dodson K, and Longest PW: Variability in Nose-to-Lung Aerosol Delivery. J Aerosol Sci. 2014;78:11-29.