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Qingguo Xu, PhD


Assistant Professor
Department of Pharmaceutics

Location:  Smith Building, Room 454C
Phone: (804) 828-6092
Email: qxu@vcu.edu
Web: Research Website

Mailing Address

School of Pharmacy - Dept of Pharmaceutics
410 N 12th Street
P.O. Box 980533
Richmond, VA 23298-0533
Fax: (804) 828-8359


Area of Focus

  • We are a new lab, looking for driven, creative individuals passionate about finding ways to fight against blindness. If you are interested in working in the Xu Lab, please contact Prof. Xu via email to check for current openings and available projects.

Education

  • Ph.D., Materials Science (University of Oxford, 2009)

Research Interests

  • Novel drug delivery systems for treating various ocular disorders, including corneal graft rejection, noninfectious uveitis, ocular neovascularization, diabetic retinopathy, age-related macular degeneration

Publications

  • Recent Publications
    • C. Schneider*, Q. Xu*, N. Boylan*, J. Chisholm, B. Tang, B. Schuster, A. Henning, L. Ensign, E. Lee, P. Adstamonghonhul, B. Simons, X. Gong, S. Wang, T. Yu, M. Boyle, J. Suk, J. Hanes, Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation, Science Advances, 2017, 3(4): e1601556.
    • A. Elgogary*, Q. Xu*, B. Poore, J. Alt, S. Zimmermann, L. Zhao, J. Fu, B. Chen, S. Xia, Y. Liu, M. Neisser, C. Nguyen, R. Lee, J. Park, J. Reyes, T. Hartung, C. Rojas, R. Rais, T. Tsukamoto, G. Semenza, J. Hanes, B. Slusher, A. Le, Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer, Proc Natl Acad Sci USA, 2016, 113(36):E5328-5336.
    • Q. Xu, L. Ensign, N. L. Boylan, A. Schon, X. Gong, J. Yang, N. Lamb, S. Cai, T. Yu, E. Freire, J. Hanes, Impact of surface polyethylene glycol (PEG) density on biodegradable nanoparticle transport in mucus ex vivo and distribution in vivo. ACS Nano, 2015, 9(9), 9217-9227.
    • Q. Pan*, Q. Xu*, N.J. Boylan, N.W. Lamb, D. Emmert, J. Yang, L. Tang, C.G. Eberhart, J. Hanes, W.J. Stark, Corticosteroid-loaded biodegradable nanoparticles for pretention of corneal allograft rejection in rats, J Control Release, 2015, 201, 32-40.
    • E. Nance, C. Zhang, T. Shih, Q. Xu, B. Schuster, J. Hanes, Brain-penetrating nanoparticles improve paclitaxel efficacy in malignant gliomas, ACS Nano, 2014, 8(10):10655-64.
    • Q. Xu, N. Boylan, B. Miao, S. Cai, H. Patel, J. Hanes, Scalable method to produce biodegradable nanoparticles that rapidly penetrate human mucus, J Control Release, 2013, 170, 279-286.
    • Q. Xu, N. Boylan, J. Suk, Y. Wang, E. Nance, J. Yang, P. McDonnell, R. Cone, E. Duh, J. Hanes, Nanoparticle diffusion in, and microrheology of, the bovine vitreous ex vivo, J Control Release, 2013,167, 76-84.